Downstream Manufacturing Scientist from Joulé

Responsibilities:

• As a Downstream Manufacturing Scientist you would be responsible for executing purification of mammalian cell-based cultures and producing recombinant proteins for a wide range of mammalian based biosimilars.
• As the Downstream Manufacturing Scientist, you will be responsible for the purification of 50L to 1000L volumes engineering, clinical and commercial batches in a cGMP environment.
• You would need to have technical expertise in AKTA purification skids or similar and Tangential Flow Filtration (TFF)
• You would need to be knowledgeable about initiating batch records, protocols, investigations and other technical documents.

Requirements:

• Bachelor's or Master’s degree in chemical, biological or biochemical sciences
• 4- 5 years of experience in the biopharmaceutical industry
• Previous experience working in a GMP and an aseptic manufacturing environment.
• Experience working with AKTA Process skids or similar
• Familiarity of single use manufacturing consumables such as bags, tube sets, columns and process manifolds
• Possess knowledge to execute engineering and clinical batches; familiar with GMP documentation.
• Basic computer skills, including knowledge of Word, Excel and spread sheet
• Knowledge of GMP batch manufacturing and packaging documentation; audit and review.
• Knowledgeable in cleaning verification/validation