End User Computing Engineer at 4D Molecular Therapeutics

Attention recruitment agencies: All agency inquiries are vetted through 4DMT’s internal Talent Acquisition team. No unsolicited resumes will be accepted. The 4DMT Talent Acquisition team must expressly engage agencies on any requisition. Agencies contacting hiring managers directly will not be tolerated, and doing so may impact your ability to work with 4DMT in the future.

 

4DMT is a clinical-stage biotherapeutics company harnessing the power of directed evolution for targeted genetic medicines. We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products. We believe key features of our targeted and evolved vectors will help us create targeted product candidates with improved therapeutic profiles. These profiles will allow us to treat a broad range of large market diseases, unlike most current genetic medicines that generally focus on rare or small market diseases.  

Company Differentiators: 

•    Fully integrated clinical-phase company with internal manufacturing
•    Demonstrated ability to move rapidly from idea to IND
•    Five candidate products in the clinic and two declared pre-clinical programs
•    Robust technology and IP foundation, including our TVE and manufacturing platforms
•    Initial product safety and efficacy data substantiates the value of our platforms
•    Opportunities to expand to other indications and modalities within genetic medicine

GENERAL SUMMARY

We seek a highly skilled and experienced Senior Infrastructure Engineer to join our dynamic team. In this role, you will be responsible for planning, designing, implementing, and maintaining our computing infrastructure to ensure a secure, efficient, and reliable digital ecosystem. You will also provide strategic infrastructure support to IT business partners, particularly in the pre-clinical and clinical areas to address their technology requirements and drive the success of critical initiatives. The Senior Infrastructure Engineer is responsible for the management of 4DMT’s:

• IT endpoint infrastructure & enterprise end user services
• IT infrastructure, including servers, cloud services, hardware systems and applications
• Planning, designing, and implementing comprehensive infrastructure solutions that meet the evolving needs of our organization

This Information Technology role reports to the head of IT Operations & Security.

RESPONSIBILITIES:

• Design, develop, implement, and manage agile, scalable, and secure enterprise-level user-centric computing solutions, including:
• High-end workstation, desktop, and laptop systems
• Mobile devices (with secure BYOD integration)
• Virtualization technologies (VDI/VM) for flexible work arrangements
• System images, software packages, and productivity/business applications
• Deploy and configure operating systems (Windows, macOS, and Linux) to meet organizational requirements, ensuring seamless compatibility, optimal performance, and adherence to stringent security standards and compliance frameworks.
• Design, develop, implement, and maintain automation scripts and workflows to automate repetitive tasks, optimize infrastructure operations, enhance user experience, and increase overall efficiency.
• Design, build, and implement comprehensive automated infrastructure management solutions, encompassing software development, deployment, configuration management, monitoring, and analytics, to optimize operational efficiency, enhance reliability, and drive business agility.
• Proactively seek out and capitalize on opportunities for automation, process optimization, and innovation, driving efficiency, productivity, and excellence in operations.
• Proactively monitor system performance, quickly troubleshoot and resolve issues, and effectively optimize resource utilization to ensure high availability, reliability, and scalability.
• Implement security measures to protect end user devices and data, including encryption, access controls, and antivirus solutions.
• Ensure compliance with regulatory requirements and industry best practices.
• Provide technical support to end users, including troubleshooting hardware and software issues, and resolving technical problems in a timely manner.
• Develop, maintain, and refine comprehensive documentation, including knowledge base articles, user guides, training materials, and technical documentation of end-user computing configurations, procedures, and policies, to empower end-users, promote self-service support, and ensure informed decision-making.
• Interact with cross-functional IT teams to assess end user computing needs and develop strategic plans for technology adoption and integration.
• Foster strong relationships with diverse stakeholders across the organization, facilitating open dialogue to capture requirements, share progress, and incorporate feedback, ensuring alignment and driving collaborative success.
• Participate in technology evaluations and recommend solutions that align with business objectives and budget constraints.
• Ensure compliance with IT policies, standards, and procedures, and participate in audits as required.
• Proactively monitor and assess emerging technologies and industry trends in end-user computing, evaluating their strategic potential, risks, and opportunities for innovation and business value, to inform organizational decisions, and drive future-ready solutions.
• Other duties as assigned, nothing in this job description restricts management’s right to assign or reassign duties & responsibilities to this job at any time.

QUALIFICATIONS: 

Education: 

• S. in Computer Science or industry-recognized technical education & experience.

Experience: 

• 7+ years' experience as user-focus infrastructure engineer delivering solutions in highly regulated, complex and multi-vendor ecosystems with a strong preference for candidates having pharma or biotech industry expertise and a deep understanding of compliance-driven environments.
• 5+ years' experience managing desktop and server OS and application patching and application packaging using sophisticated management systems (e.g. Intune, System Center Configuration Manager)
• 7+ years' experience supporting Windows Enterprise customers in a large-scale (300+ node) environment.
• 5+ years biopharmaceutical experience in fast-growing environment.

Skills

• Successful track record of infrastructure architecture and administration, execution, and delivery.
• Ability to multi-task in a fast-paced, dynamic environment.
• Experience working in a regulated networking environment (SOX and 21CFR11).
• Excellent organizational, communication and customer service skills with active-listening skills.
• Proven adaptability to shifting project schedules, priorities, and assignments; able to make effective decisions under pressure.
• Demonstrated problem-solver with the ability to cope under pressure and coordinate multiple activities in a dynamic, fast-paced team environment.
• Excellent written and documentation skills including proof reading and attention to detail.
• Hands-on experience with hardware and software troubleshooting, system imaging, and software deployment tools.
• Must be a self-driven, motivated IT professional with strong analytical and problem-solving skills, and ability to diagnose and resolve complex technical issues.
• Excellent communication and interpersonal skills, with the ability to work effectively in a team environment and interact with diverse stakeholders including executive management.
• Proactively identify opportunities for process improvements and automation to streamline end-user support services.
• Proficient in automation technologies, including Pipeline Pilot, MS Power Automate and additional scripting languages, with a strong ability to leverage scripting expertise to streamline processes, enhance efficiency, and drive operational excellence.
• Comprehensive expertise in operating systems (Windows, macOS, Linux), virtualization technologies (e.g., VMware, Citrix Virtual Apps and Desktops), and endpoint management solutions (e.g., Microsoft Intune, SCCM, Tanium), M365, Okta, Active Directory, etc.Skills: 

Base salary compensation range: $57.69/hr - $83.17/hr

Please note, the base salary compensation range and actual salary offered to the final candidate depends on various factors: candidate’s geographical location, relevant work experience, skills, and years of experience. 

 

4DMT provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, genetic information, marital status, status as a covered veteran, and any other category protected under applicable federal, state, provincial and local laws. Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities