Modeling and Simulation Scientist, PK/PD & Pharmacometrics at Eli Lilly and Company

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Lilly is on the forefront of groundbreaking research and the portfolio encompasses small molecules, peptides, antibodies, genetic medicines, RNA therapeutics, and more. The PK/PD organization uses a variety of model-based approaches including PBPK, PK/PD, QSP and pharmacometrics to impact across this portfolio from early discovery to clinical submission and beyond.

We seek dynamic, energetic, curious, and collaborative quantitative scientists ready to engage and work on life-changing therapies for patients. You will interact with cross-functional teams applying a variety of in silico approaches to inform drug discovery and development. Through engagement in experimental design and data interpretation, you will help drive and deliver the discovery and/or development portfolio.

We are passionate about developing our people to their full potential and making a real impact on patients' lives. Apply today to join Team Lilly!

You will develop and apply quantitative models to support the discovery and development of therapeutic drug candidates. We are looking for scientists with expertise in modeling and simulation to join our team. You’ll use various analytical and computational tools to understand the factors that influence the pharmacokinetic and pharmacodynamic properties of our drugs. We need a dynamic and driven scientist who will:

• Integrate quantitative approaches into drug discovery and/or development
• Conduct modeling and simulation to inform drug discovery and/or development programs.
• Communicate quantitative data, both internally and in the scientific community
• Provide scientific leadership to project teams in selecting the right target, molecule, dose, patient population, and development strategies.

• PhD in DMPK, Pharmacometrics, Pharmacokinetics/Pharmacodynamics, Pharmaceutics, Biology, Computational Sciences, Engineering, Chemistry, Statistics, Toxicology or a related subject area
• Or, MS and at least 5 years industry or academic experience in PBPK, QSP, PK/PD, exposure-response modeling, clinical trial simulation, drug-drug interactions, special populations, or other modeling & simulation related field

• Experience using relevant software such as Phoenix, NONMEM, R, SimCYP, Gastroplus, Monolix, Python, MATLAB, or similar
• Adept at working with cross-functional colleagues
• Thorough understanding of pharmacokinetics and/or pharmacodynamic principles along with an ability to clearly communicate theories and concepts.
• Excellent self-management and organizational skills
• Demonstrated strong communication skills

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

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