Principal Research Scientist I, Computational Chemistry Platform at AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.

The DNA-encoded Library (DEL) platform group at AbbVie Headquarters in Lake County, Illinois, is seeking a highly talented and motivated scientist to enhance our in-house DEL data computational and analysis capabilities to support our drug discovery efforts in the Small Molecule Therapeutics and Platform Technologies (SMTPT) department. The individual will work collaboratively with cross-function software engineering, hardware support, and cheminformatics teams to leverage technical expertise to drive our DEL informatics pipeline. The successful candidate should possess strong communication and leadership skills and is expected to contribute to drug discovery projects across the therapeutic area portfolio of AbbVie interests.

Key Responsibilities:

• Strategic leadership for developing infrastructure and workflows for DEL platform via working cross functionally with engineers, computational scientists and cheminformatics.
• Responsible for enhancing DEL data integration processes, including DEL compounds management.
• Drive developments of new computational tools and methodologies (e.g., machine learning models, data exploration and visualization) to strengthen our DEL data analysis platform. Serve as a key contributor to synergize computational efforts across teams designing and screening DNA-encoded libraries.
• Accountable for developing and implementing cutting-edge computational tools and software applications through both internal and external collaborations.
• Ensure optimal cross-functional relationships in a matrix environment within AbbVie SMTPT organization.
• Provide DEL informatics expertise, updates on project status, and recommendations to our leadership.

• Ph.D. in Computational Chemistry, Medicinal Chemistry, or related discipline with 6+ years industrial experience or masters degree with 12+ years of experience in the Drug Discovery industry
• Extensive knowledge and experience in design and implementation of engineering solutions applied to Drug Discovery projects required.
• Excellent knowledge and understanding of DEL technology.
• Experience in data mining, database management, statistical analysis of large data sets
• Expertise with scripting languages and machine learning methodologies is desirable.
• Excellent written and oral communication skills, strong organizational skills with attention to detail
• Strong interpersonal and collaborative skills to work in a team-oriented, matrix environment
• Motivated, independent, creative, and productive problem solver with a proven ability to advance new scientific concepts.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location,andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible to participate in our short-term incentiveprograms.

• This job is eligible to participate in our long-term incentiveprograms

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's soleandabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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