Senior Manager, Site Supply Chain, Allogeneic Cell Therapy at Neogene Therapeutics

At AstraZeneca's Oncology R&D division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

Position Summary

The Sr. Manager, Site Supply Chain will oversee supply chain operations for our allogeneic cell therapy product and manufacturing site. You will start up the operations to manage the end-to-end supply chain activities related to allogeneic cell therapy products, ensuring the delivery of high-quality products to patients while maintaining compliance with regulatory standards. You will report to the Vice President of Supply Chain. Important responsibilities include:

Responsibilities

• You will create and execute allogeneic cell therapy supply chain processes for:
• Demand and supply planning: collaborate with teams to forecast demand and develop production supply plan to meet clinical trial requirements
• Inventory management of Raw Materials, Gene Editing Tools and Final Product: optimize inventory levels to ensure uninterrupted development, production and patient supply
• Healthy Donor starting material and supplier management: oversee supplier relationship and manage unique planning requirements for allogeneic patient starting material
• Labeling and Packaging: determine final product cryogenic labeling, packaging and shipping solutions
• Storage, logistics and distribution: determine allogeneic final product storage and logistics to the clinical site. Contribute to the Investigational Product Handling Manual and training.
• You will create and start up brand new manufacturing site supply chain processes for Materials Management, Warehouse, Product Distribution, Production Scheduling, and other site operations
• You will ensure raw material GMP readiness, including new materials risk framework, risk assessment and mitigations for allogeneic cell therapy requirements
• You will author site supply chain SOPs, work instructions, and management tools for managing site supply chain operations.
• You will set up ERP system and master data readiness for warehouse and inventory management
• You will support tech transfer, launch of clinical trial and new facility readiness
• You will have future managerial responsibilities

Education and Experience

• 8+ Years with BS/BA OR 6+ Years with MS/MA or MBA, OR 3+ Years with PhD
• Direct experience and working knowledge in the pharmaceutical or biotech industry, with experience in supply chain logistics and planning, manufacturing site supply chain experience, and preferably cell therapy experience
• Knowledgeable with cGxP for cell therapy and pharmaceutical industry.
• Experience using inventory management, asset management and environmental monitoring systems such as ERP (Netsuite), CMMS (Blue Mountain) and EMS (Vaisala).

The anticipated salary range for candidates who will work in Santa Monica, CA is $129K to $157K. The final salary offered to a successful you will be dependent on several factors that may include the type and length of experience in the job type and length of experience within the industry, education.

This position is based in Santa Monica, CA with at least three days per week onsite. We balance the expectation of being in the office while respecting individual flexibility.

Benefits

• Short-term incentive bonus opportunity
• Equity-based long-term incentive program
• 401(k) plan
• Paid vacation and holidays; paid leaves
• Health benefits including medical, prescription drug, dental, and vision coverage.

DE&I Statement

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.