Senior Scientist I, Engineering - AbbVie
North Chicago, IL
About the Job
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.
Job Description
Process Engineering, a part of AbbVie R&Ds Small Molecule CMC Development organization, is responsible for designing and developing scalable processes to make small molecule drug substances and drug products, including antibody drug conjugates (ADCs), throughout pre-clinical and clinical development stages. Process Engineering also partners with Biologics CMC Development and Aesthetics R&D functions to provide active engineering support to enable robust process scale-up and manufacturing of biologics drug substances and drug products, including toxins and cosmetic active ingredients (CAIs). We contribute to the development of innovative engineering technologies and create valuable intellectual property through the composition of matter, chemical processes, and technologies resulting in cost-effective commercial manufacturing processes. We support the development of the supply chain for pipeline molecules and help prepare and defend CMC regulatory content.
Chemical/Bio Engineers support pipeline projects through all phases of development. Early in development, engineers focus on ensuring that the process can be run safely, identifying and addressing scale-up issues, enabling processes that can be scaled-up successfully. In the later stages of development, engineers optimize the drug substance and drug product processes and lead manufacturing campaigns. Engineers also work cross-functionally to transfer the optimized process to manufacturing sites, develop control strategy, and prepare reports to support regulatory filings.
The successful candidate will play a key role in the R&D Process Engineering function, specifically the Center for Reaction Engineering. The core deliverable of the function is to develop robust commercial processes to manufacture small molecule APIs and ADCs. As a member of the Center for Reaction Engineering, the selected candidate will have a strong background in chemical reaction engineering and is expected to address challenging problems with chemical reactions using expertise in chemical kinetics, transport phenomena, mathematical modeling, and reactor design. The candidate is also expected to lead identification and development of novel technologies to enhance efficiency in process development, scale-up, and commercialization. Such technologies may include deployment of custom automation solutions, fit-for-purpose reactor configurations, and novel modeling approaches. The candidate must exhibit a collaborative nature in identifying process challenges on a wide range of projects, participate in a cross-functional team of chemists and chemical engineers to deliver specific project needs, and take on a leadership role in developing and implementing solutions.
Qualifications
Basic Requirements:
- BS, MS, or PhD in Chemical Engineering or a related field and 10+ (BS), 8+ (MS), or 0+ (PhD) years of relevant industrial experience required.*
- Candidates are expected to have a strong background in chemical engineering and a proven ability to demonstrate their skills in these fields.
- The candidate is required to possess effective oral and written communication skills and be a strong team player.
*Job level will be commensurate with academic experience and work experience.
Preferred:
- Experience with laboratory experiments and process scale-up.
- Familiarity with operation of chemical process equipment and systems.
- Working knowledge of various analytical tools (HPLC, GC, FTIR, NMR, etc.) and integration of process analytical technologies into equipment set-ups.
- Design of scale-down reactor systems.
- Experience with various programming languages (MATLAB, Python, etc.) and kinetic modeling tools.
- Understanding of cGMP.
Key Leadership Competencies:
- Builds strong relationships with peers and cross-functionally with partners outside of team to enable higher performance.
- Learns fast, grasps the essence, and can change course quickly where indicated.
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment, open to suggestions and experimentation for improvement.
- Embraces the ideas of others, nurtures innovation, and manages transforming innovation to reality.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
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