Senior Scientist, Small Molecule Analytical Sciences - AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. 

Job Description

Technology and Therapeutic Platforms has an exciting opportunity for a Senior Scientist to join the Small Molecule Analytical Sciences (SMAS) team at AbbVie.  The SMAS team is a global organization that provides enabling technologies to support Discovery Medicinal Chemistry initiatives. The scientist will join the Analytical and Purification Sciences group to execute High-Throughput Chemistry compound library purification and analysis and devise innovative solutions to complex analytical and separation problems through the implementation of sophisticated instrumentation. The candidate will act as a lead scientist and liaison in working with the High-Throughput Chemistry team, and critically evaluate relevant scientific advances and integrate this knowledge into research programs.

Key Responsibilities

• Execute purification of high-throughput chemistry compound libraries using preparative HPLC-MS to support small molecule drug discovery projects.
• Collaborate with high-throughput Chemistry team through developing methods and providing technical guidance to solve analytical and purification problems.
• Collaborate within Analytical and Purification Sciences group to develop efficient workflows for sample prioritization and client communication.
• Proactively mentor colleagues in technical development and in establishing positive and productive working relationships.
• Maintain analytical and preparative HPLC and MS instrumentation and independently troubleshoot instrument problems.
• Maintain a high level of productivity in the laboratory setting.
• May supervise one or more direct reports
• Keep abreast of current literature and industry trends to assess new approaches in high-throughput purification and analytical technologies. Propose and implement new initiatives/directions for the team.
• Maintain a highly productive high-throughput purification workflow, establish strategies that effectively optimize available equipment and personnel, and promote efficiency and enable new paradigms in high-throughput Chemistry.
• Demonstrate a high degree of responsibility in maintaining scientific standards and safe laboratory practices.
• Keep accurate and current records of research and/or project related activities according to AbbVie policies.

Qualifications:

Position will be hired based on level of experience.
Senior Scientist I or Senior Scientist II.

• PhD or MS in Organic Chemistry, Analytical Chemistry, or related fields with 0-4+ years (PhD); 8-10+ years (MS); or 10-12+ years (BS) of postdoctoral and/or pharmaceutical industry experience.
• Hands-on experience with analytical and preparative scale HPLC and LC-MS
• Ability to operate and troubleshoot a variety of analytical and preparative instrumentation hardware and software.
• Demonstrated record of achievement in purification on milligram to gram scale for a variety of programs using multiple approaches and technologies.
• Knowledge of synthetic organic chemistry and the ability to communicate effectively with high-throughput chemistry team.
• Proven effective written and verbal communication skills and ability to interact with scientists and engineers.

Preferred

• Experience of working in a fast-paced purification group and communicating effectively with Medicinal Chemistry teams.
• Experience in developing workflows for high-throughput chemistry analysis and purification.
• Experience with instrument development, automation, and/or programming.

Key Leadership Competencies

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance
• Learns fast, grasps the "essence" and can change course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others, nurtures innovation and manages to reality

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs. 
• This job may be eligible to participate in our long-term incentive programs

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html