Analytical Scientist - Apex Systems

Job#: 2041032

Job Description:

Seeking a Scientist to join a growing Biotech company in the Lansdale, PA area. 
 
Key Responsibilities: 
The primary responsibilities of this position include, but are not limited to: 

• Work independently and as part of an interdisciplinary team to support the development and evaluation of non-viral gene therapies using the company’s novel technology. 

• Molecular characterization of biomolecules including DNA-conjugated modalities including peptides, antibodies, proteins, and small molecules. 
• Test various molecules and modalities for biochemical suitability, potential efficacy and safety using cell-based assays combined with various analytical methods.
• Develop cell and molecular assays to assess cell fate, potency and durability of the delivery scaffold and genetic payloads. 
• Design and test cell-based protocols for transfer to the Development team. 
• Maintain data acquisition and analysis in electronic laboratory notebook. 

 
Basic Qualifications: 

• BS degree in Cell Biology, Molecular Biology, Biochemistry, Pharmaceutical Sciences with 3-5 years or a MS degree with 0-3 years of research and development experience.   
• Experience with mammalian cell culture and knowledge on cell based assays.
• Detail-oriented with strong organizational and communication skills. 
• Experience with DNA and RNA extraction methods and downstream use.  
• Hands-on experience with standard laboratory equipment and procedures. 
• Able to digest complex articles and reviews and pull relevant information, ideas, and methodologies for experimental use. 
• General understanding of cell-based assays and outcomes. 
• Knowledge of peptide and protein structure and function. 
• Basic analytical characterization methods. 

 
 
Preferred Skills/Experience: 

• Experience with flow cytometry cell-based assays for quantitative assessment of results. 
• Experience with qPCR, ddPCR and other qualitative and quantitative nucleic acid analysis methodologies. 
• Experience in performing plate and bead-based pulldown and analytical assays.
• Able to troubleshoot experiments and instrument issues. 

 

 

 

 

 

 

 

 

EEO Employer

Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at [email protected] or 844-463-6178.