Associate Director, Data Science - Neuroscience Discovery - Johnson and Johnson

Johnson & Johnson Innovative Medicine is currently seeking an Associate Director, Data Science - Neuroscience Discovery with a strong preference for this individual to be located at one of our sites in Titusville, NJ, Cambridge, MA, or La Jolla, CA. (Remote work options within the US may be considered on a case-by-case basis and if approved by the company.)

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/ .

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges.

We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.

At Johnson & Johnson, we all belong.

In the role of Associate Director, this outstanding leader, data scientist and bioinformatician will work to optimize our Discovery portfolio. Envisioning the future, you will establish the earliest data science and digital health strategy per compound, that will evolve over the development lifecycle. You will be part of our impactful, cross-functional team of data science leaders with diverse expertise driving value end-to-end across our pipeline from discovery through development, using molecular, digital, imaging and real-world data. This role requires knowledge of sophisticated analytics, bringing to bear bioinformatics, artificial intelligence and machine learning as needed to link molecular data (genetics, gene expression, proteomics) to brain circuitry (e.g. tissue specific, cell type specific, circuit specific expression), mechanisms of action and disease endophenotypes.
Key Responsibilities:

The candidate will focus on the Neuroscience Discovery portfolio, establishing the strategy and processes for evaluating data science and digital health opportunities. This will be achieved by leading internal and external talent to map therapeutic targets to genetics and brain biology to understand opportunities within different indications or patient populations. You will contribute to broader initiatives integrating multi-model data through AI/ML to impact at target identification and precision medicine across a range of Neurodegenerative and Neuropsychiatric diseases.

The candidate's work will be tightly coupled with our Neuroscience Discovery and Translational Medicine, Population Analytics, and other Johnson & Johnson Innovative Medicine Data Science teams.

• Create the strategy and process for evaluating therapeutic targets and precision biomarkers from the perspective of genetics, brain biology, and mechanism, drawing upon a combination of internal and external resources.
• Collaborate with scientists and clinicians to create the initial data science and digital health strategy for Neuroscience targets in discovery, being forward looking and foreseeing the path to launch.
• Contextualize target gene expression in the context of the neural circuits and cell-types underlying CNS diseases and phenotypes.
• Apply diverse data sources to evaluate opportunities across potential indications.
• Remain current on the constantly evolving landscape of neuroscience, neurodegeneration, neuropsychiatry, genomics, bioinformatics and AI/ML research in search of better strategies for prioritizing our portfolio based on biological insights.

• PhD with 6 years of progressive experience in a computational or physical science with prior experience applying data science to life sciences is required. (A degree in a biological science with extensive application of data science methodologies will also be considered.)
• Extensive background working hands-on deriving insights from high-dimensional molecular data - particularly genetic, RNAseq, proteomic and/or single cell data is required.
• Track record of scientific contributions in this field with first author publications in high-impact journals is required.
• Prior experience working in the context of target discovery and validation in a pharmaceutical company is required.
• Experience translating data into strategies and executable action plans is required.
• Strong reputation for driving novel solutions to problems and providing strategic advice is preferred.
• Experience in leading interdisciplinary teams through either people or project leadership is required.
• Experience working with both discovery scientists and clinicians is preferred.
• Ability to clearly communicate technical work to a diverse audience is required.
• Background and experience working in Neuroscience is strongly preferred.
• Familiarity with clinical development processes is preferred.
• Up to approximately 10% yearly travel is required (International, Domestic).

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability. The anticipated base pay range for this position is $118,000 to $203,550. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis.

• Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
• Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).
• This position is eligible to participate in the Company's long-term incentive program.
• Employees are eligible for the following time off benefits:
• Vacation - up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
• Holiday pay, including Floating Holidays - up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year
• Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.

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