Bioactivity Assay Development Consultant - Kikiktagruk Inupiat Corporation

Title: Bioactivity Assay Development Consultant

Location: Bethesda, MD (Telework available)

Status: Part-Time

Travel: Some travel required

Position Summary:

The Bioactivity Assay Development Consultant will provide Assay Development consulting support services to the NIH Blueprint Neurotherapeutics Network.

Duties and Responsibilities:

• The Bioactivity Assay Development Consultant will serve on the NIH BPN Lead Development Teams.
• Work on a number of projects in the exploratory through preclinical safety stages. Some projects may proceed to investigational new drug (IND) and clinical trial stages.
• Offer input on project milestones, development strategy, study design, and data interpretation.
• Assay Development expertise and contribute feedback and guidance on projects to the NIH and to LDT members through conference calls and by email.
• Evaluate bioactivity assays and recommend strategies and experiments to optimize and/or validate the assays for use in a medicinal chemistry campaign.
• Assist in the establishment of milestones related to assay optimization or validation.
• Provide guidance on the design and interpretation of commonly used in vivo assays, such as cognitive and behavioral tests.
• Serve as the assay development expert to identify potential developmental challenges and suggest strategies to address these challenges on realistic timelines.
• Partner with other consultants, contractors, and the NIH staff, advise, strategically plan, and manage programs to facilitate lead optimization, IND enabling, and clinical studies.
• Serve as a resource to lead development team members for assay requirements, and logistics to conduct drug development activities for small molecule compounds from the preclinical stage through to the initial clinical stage.
• Partner with other consultants, contractors, and the NIH staff, advise, strategically plan, and manage programs to facilitate lead optimization, IND enabling, and clinical studies.
• Serve as a resource to lead development team members for assay requirements, and logistics to conduct drug development activities for small molecule compounds from the preclinical stage through to the initial clinical stage.
• Collaborate on the design of investigative studies in support of development compounds.

Minimum Requirements:

Education and Industry Experience

• A minimum of 15 years of experience in assay development in pharmaceutical industry.
• Experience in developing, implementing, and optimizing cell-based and biochemical assays for high throughput screening and safety screening.
• Experience in the application of assays in industrial pharmaceutical discovery and development; application of automated technologies and robotics relevant to pharmaceutical assays and application of diverse range of molecular and cellular techniques in pharmaceutical assays.
• Experience managing or being a senior leader in drug discovery and development projects in the biopharmaceutical industry. Experience with drug discovery and development for nervous system conditions is required.
• Experience working with multi-disciplinary teams at a senior level in the biopharmaceutical industry, especially teams with members from outside organizations and members at various management levels.
• Experience in team leadership, consulting, or service on strategic and advisory boards will be considered.
• Experience working with multi-disciplinary drug development teams at a senior level in the pharmaceutical industry.
• Experience with drug discovery and development of small molecules for nervous system conditions is required.
• Broad experience across the entire drug discovery and development process is especially desired.
• Biologics experience is a plus

Knowledge, Skills, and Abilities

• Ability to work in a virtual, cross-functional team environment and manage competing priorities.
• Must have strong interpersonal skills, an attention to detail, excellent organizational, writing, communication, presentation and documentation skills as well as computer and software literacy.

Certifications/Licenses/Other

• An advanced degree in an appropriate scientific discipline is required.

Benefits:

KIC offers a comprehensive benefits package to eligible full-time employees including: Medical, Dental, and Vision Insurance, 401k with Match, Life and ADD Coverage, Short and Long Term Disability, Paid Time Off and Holidays, Education Assistance/Tuition Reimbursement, Employee Assistance Program, Employee Discount Program, and more!

Apply online at our website: https://kikiktagruk.applicantpool.com/

Disclaimer:

This is not to be an exclusive list of all responsibilities, duties, and skills required of the person in this job. KIC is an Equal Opportunity Employer. KIC considers all applicants for employment without regard to race, color, sex, national origin, religion, age, physical or mental disability, family responsibility, marital status, sexual orientation, political affiliation, veteran's status, gender identity, or any other legal protected status.

Please view Equal Employment Opportunity Posters provided by OFCCP here (http://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm).

Pursuant to The Alaska Native Claims Settlement Act 43 U.S.C. Sec. 1601 et seq., and federal contractual requirements, Kikiktagruk Inupiat Corporation, may legally grant certain preference in employment opportunities to KIC Shareholders, and their Descendants.

Successful candidate must pass, comply, and adhere to KIC's Drug and Alcohol policy/testing requirements and may be required to pass a background and/or Motor Vehicle Records check.