Computational Research Scientist, Deep Learning - Manus

Waltham, MA 02453

Computational Research Scientist, Deep Learning

Manus

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better

performing and more sustainable versions of complex molecules traditionally sourced from plants,

animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death

between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic

biology today. We are seeking a motivated individual for a Computational Research Scientist position

that will specialize in deep learning to solve biological problems. This candidate should have experience

in at least one area of deep learning but have familiarity with a broad array of techniques, such as data

pipeline development, metabolic engineering, or protein engineering. This person will play an integral

part of Manus Bio’s R&D team contributing to deep learning and AI tool development to create better

enzymes, microbes, and bioprocesses to produce more sustainable BioAlternative products.

Why work at Manus Bio:

Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that come with working on the cutting edge.

Responsibilities:

Develop and implement deep learning models to predict and optimize enzymes and metabolic pathways in microbial systems.
Conduct simulations and modeling of metabolic networks to identify key regulatory nodes and potential engineering targets.
Perform protein variant designs with established protocols to support in-house projects.
Collaborate with experimental biologists to design and interpret experiments that validate computational predictions.
Communicate results and insights to multidisciplinary teams, including presentations and written reports.

Required qualifications:

Ph.D. in Bioengineering, Biochemistry, Biostatistics, Chemical Engineering, Computer Science, or similar discipline, with a strong focus on deep learning and/or cell engineering
Proven experience with deep learning frameworks (e.g., TensorFlow, PyTorch) and libraries.
Proficiency in programming languages such as Python, R, or MATLAB
Excellent communication skills, both written and verbal

Preferred qualifications:

Familiarity with metabolic engineering and synthetic biology principles
Knowledge of metabolic flux analysis and constraint-based modeling (e.g., FBA, COBRA toolbox)
Knowledge of protein structural modeling and prediction
Experience in industrial biotechnology or a related industry

Preferred Working Style:

Must be very well-organized and be able to handle multiple projects simultaneously.
Must be a quick learner who is self-motivated and able to ask questions and seek clarity.
Must be flexible with day-to-day duties and able to thrive in a start-up environment.
Must be an excellent team member with strong communication skills and a desire to work collaboratively.
Must hold themselves to the highest professional, scientific and ethical standards.

Source : Manus