Principal Associate Scientist, Compound Management and Lab Automation - Parabilis Medicines

Why join us?

Parabilis Medicines (formerly FogPharma) is a biopharmaceutical company pioneering the discovery and development of Helicon™ therapeutics, which are peptides capable of efficient cell entry and modulation of both protein-protein and protein-DNA interactions. Through Helicon therapeutics, Parabilis is poised to revolutionize the medical possibilities for patients by precisely drugging intracellular targets long understood to be significant drivers of disease but never before drugged due to the limitations of existing drug modalities to act within the cell.

FOG-001, the company's first-in-class TCF-blocking β-catenin inhibitor, is being evaluated in a Phase 1/2 study for patients with advanced solid tumors, including colorectal cancer. Parabilis is fully leveraging the unprecedented potential Helicons present by deploying proprietary, custom-built machine learning and computational methods as part of its discovery and development process. Parabilis Medicines has raised more than $500 million to date from leading life sciences investors. Parabilis is headquartered in Cambridge, Mass.

What's the opportunity?

We are seeking an enthusiastic, highly motivated, detail-oriented and flexible individual with compound management experience to work within our Discovery Sciences group. The successful candidate will play a crucial role by using state-of-the-art automated instrumentation to deliver high quality compound formats in vials, tubes, and plates for testing in all our discovery programs as well as tracking Parabilis's entire compound collection.  Moreover, the candidate will drive identification and implementation of new automation solutions to support research needs. This role, reporting to our Associate Director of Research Operations, requires excellent organization, time management, problem solving, and communication skills.

• Fulfillment of internal compound requests in a timely manner.
• Operating and troubleshooting bench top instruments as well as automated liquid handling systems.
• Continuous improvement and automation of compound management workflows in collaboration with research teams.
• Coordinate with research informatics to maintain and update compound inventory in LIMS as part of compound management workflows.
• Communicating with stakeholders to ensure an efficiently run operation and data integrity.
• Maintaining regular upkeep in compound management workspace including compound management consumables and instrument maintenance schedules.

What you'll need to be successful:

• BS or MS in Chemistry, Biology, Engineering, or related field and10+ years of laboratory experience in life sciences
• Highly  organized with a very high attention to detail in  inventory tracking  and file management.
• Extensive experience in robotics/automation and LIMS
• Excellent analytical, time management, and communication skills.
• Team player with collaborative, solutions-oriented mindset and strong communication and interpersonal skills
•  Positivity, leadership, adaptability, adventurousness, and excitement to work in a dynamic, goal- and performance-oriented team environment.
• Able to work on-site and attend in-person meetings .

Core Values

Parabilis Medicines is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit.

• Creative. We are creating a whole new class of medicine requiring creativity to solve challenges as they arise, which we have successfully done since the inception of the company.
• Patient-focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact.
• Execution-oriented. As we begin clinical development and large-scale manufacturing, the team is balancing creativity and nimbleness with relentless, rigorous and flawless execution.
• Humble. We fully appreciate that science and technology and policy are in flux, and we balance deep experience with humility to ask fundamental questions and seek newly available solutions.

As an equal opportunity employer, Parabilis Medicines values diversity and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

30 Acorn Park Drive    |     Cambridge, MA 02140    |    www.parabilismed.com