Principal Research Scientist, Bioinformatics Engineering Group Lead at AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.

AbbVies Genomic Research Center (GRC) is a center of excellence for bioinformatics, functional genomics, and human genetics. The GRC works across all R&D including discovery and clinical development, supporting all of AbbVies therapeutic areas and multiple areas such as process sciences, global epidemiology, search and evaluation, and corporate strategy.

We are seeking a talented and highly motivated individual to join our team as a Bioinformatics Engineering Group Lead. As a key member of the critical Bioinformatics Engineering (BE) team in the GRC, you will play a pivotal role in driving high throughput omics data generation and ensuring top-notch quality control. With the opportunity to provide effective leadership, this position is based at AbbVie's Lake County Illinois headquarters, offering an inspiring environment for your career advancement and personal growth.

Responsibilities:

• Lead the Bioinformatics Engineering Group, providing expert technical guidance, overseeing task delegation, conducting performance evaluations, and fostering career development for team members.
• Take ownership of individual contributions and projects, including project design, gathering requirements, developing code and systems, and ensuring comprehensive documentation.
• Address the NGS data production engineering needs of the GRC by managing data, developing pipelines, automating processes, and scaling operations.
• Serve as a crucial liaison between AbbVie's research-serving IT teams and GRC Genomic Technologies and Bioinformatics organizations, advocating for technical requirements relating to infrastructure development, and facilitating seamless collaboration.
• Collaborate with the Bioinformatics Engineering Leadership Team to shape and execute strategic plans, ensuring the continuous evolution and growth of the department to meet the demands of a fast-paced and dynamic research environment.
• Stay up-to-date with the latest advancements in AI and leverage them to enhance our capabilities, while also providing the opportunity to foster innovation, exploration, and personal growth.

Requirements:

• BS with typically 14-16+ yrs, MS with typically 12-14+ yrs, or PhD with typically 6-8+ yrs of relevant experience, and degree in Bioinformatics, Computer Science, or relevant field.
• Proven experience in personnel leadership, with a track record of directly supervising a minimum of 2 employees.
• Extensive expertise in bioinformatics analysis of NGS data, including a strong command of tools and algorithms for basecalling, demultiplexing, quality control, and reporting. Preference will be given to candidates with experience in a CLIA environment.
• Exceptional knowledge of Illumina NGS data generation platforms, along with familiarity with Oxford Nanopore or other long-read technologies.
• In-depth understanding of genomics data formats, databases, and resources, such as NCBI, Ensembl, and UCSC Genome Browser.
• Demonstrated proficiency in Nextflow development and management, specifically in automating and scaling NGS and bioinformatics processes (e.g., base calling, QC, report generation). Preference for candidates with Nextflow Tower experience.
• Expertise in operating within both on-prem and cloud Linux HPC environments, showcasing hands-on experience across a range of AWS services (e.g., EC2, S3, DynamoDB, RDS) and data lake technologies (e.g., Snowflake, Cloudera, Databricks).
• Mastery of Python and BASH programming languages, familiarity with the software development lifecycle, and experience in applying common development patterns (e.g., microservices).
• Proven involvement in code reviews, either as a participant or a leader.
• Proficiency in version control systems (e.g., Git) and collaborative coding workflows, as well as experience with CI/CD processes.
• Excellent communication and leadership skills, with the ability to effectively communicate complex bioinformatics concepts to both technical and non-technical stakeholders, and to mentor and guide team members in their professional development.

Position will be hired based on level of experience.
Principal Research Scientist I orPrincipal Research Scientist II

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible to participate in our short-term incentiveprograms.

• This job is eligible to participate in our long-term incentiveprograms

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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