Process Development Associate Scientist - Cellular Sciences / Biosafety Development - Amgen

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At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Associate Scientist - Cellular Sciences / Biosafety Development

What you will do

Lets do this! Lets change the world!

In this vital role you will join our Biosafety Development (BSD) group in Thousand Oaks Cellular Sciences Department.

The Associate Scientist will support ensuring patient safety by performing molecular assays and viral clearance assessment studies for Amgens pharmaceutical products. Also, they will partake in technology development for detection and identification of adventitious agents of any type.

Primary focus will be on model virus production via characterized cell lines and use of these model viruses to perform GMP Viral Clearance studies supporting IND and MA filings to the FDA. Test articles are generated with protein purification processes using AKTA Unicorn HPLC methods involving all modes of chromatography (e.g. affinity, ion exchange, hydrophobic, mixed mode) Assays performed for the detection of viruses include cell-based assays and/or molecular techniques.

Responsibilities may include the following:

• Maintenance of mammalian cell lines, infection of cells with viruses and detection using cell-based or molecular methods (e.g., qPCR, NGS).

• Leading and executing GMP Viral Clearance studies to support IND and MA filings to the FDA.

• Utilizing molecular assays for the detection of other adventitious agents, including mycoplasma, bacteria, or fungus.

• Applying chromatography techniques for the purification or removal of viruses.

• Molecular assay method development and qualification.

• Training other employees.

• Managing materials and supply inventory.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dedicated professional we seek is a collaborative partner with these qualifications.

Basic Qualifications:

• Bachelors degree and 3 years of Scientific experience OR

• Masters degree and 1 year of Scientific experience

Preferred Qualifications:

• Hands on experience with maintenance of cell culture lines.

• Hands on experience with molecular biology techniques including qPCR; method development experience a plus.

• Hands on experience with purification systems, including but not limited to AKTA Chromatography system.

• Possess strong written and verbal communication skills and a desire to learn new scientific concepts.

• Work as a member of a small team to follow and develop methods.

• Demonstrate good planning and project execution skills.

• Clearly and concisely interpret and present data.

• Ability to understand, apply and evaluate cell biology, virology and mathematical principles.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans

• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.