Research Associate II/Sr Research Associate, In Vitro Pharmacology - Keros Therapeutics
Lexington, MA
About the Job
Keros Therapeutics is a public, clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel treatments for patients suffering from hematological and musculoskeletal disorders with high unmet medical need. We are a leader in understanding the role of the transforming growth factor-beta, or TGF-ß, family of proteins, which are master regulators of red blood cell and platelet production as well as of the growth, repair and maintenance of muscle and bone. We have leveraged this understanding and developed a discovery approach to generate large and small molecules to address diseases of these tissues. Targeting TGF-ß signaling pathways has been clinically proven to elicit robust changes in blood cells, muscle, and bone, which we believe provides a precedent and strong rationale for our strategy.
Job Summary: The in vitro pharmacology team is looking to hire a Senior RA to help develop cell models in relation to our neuromuscular (KER-065) and pulmonary arterial hypertension (KER-012) programs.
Primary Responsibilities:
- Execute a wide array of experiments in cellular and molecular biology.
- Perform cell culture routinely; establish and characterize innovative cell lines for disease modeling and pharmacology studies.
- Develop protocols for diverse assays, meticulously documenting and sharing research findings with colleagues.
- Actively contribute to the design and troubleshooting of experimental studies, nurturing collaboration with biology teams and cross-functional project groups.
- Provide essential support for the daily operations of biology labs.
Qualifications:
- M.S. or B.S. in cell biology or related disciplines.
- 3-6 years of hands-on experience in cellular and molecular biology techniques, including but not limited to: primary cell culture, RT-qPCR, western blotting, siRNA/shRNA silencing, CRISPR/CAS9 knockout, plasmid construction and preparation, lentiviral/retroviral transduction, SPR, flow cytometry, and ELISA-based assays.
- Proficiency in cell culture techniques, including both immortalized cell lines and primary cells.
- Previous exposure to organoids or multicellular culture models is highly regarded.
- Effective communication skills and ability to present data is required.
Our Diversity, Equity & Inclusion Mission Statement: Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.
Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.
