Research Scientist, Precision Oncology - Aitia

Job Title: Research Scientist, Precision Oncology

Location: Somerville, Massachusetts

Company Overview

Aitia is an AI-enabled biotechnology company deploying causal AI and creating Gemini Digital Twins to discover the next generation of breakthrough drugs in neurodegenerative diseases and oncology, including a lead program in Huntington’s disease. By leveraging the convergence of multi-omic patient data, high-performance computing, and causal AI, Aitia’s Gemini Digital Twins reveal the hidden biological mechanisms of disease to transform the discovery and development of new therapeutics. To date, Gemini Digital Twins have been used to accelerate R&D in oncology, neurodegeneration, cardiometabolic, and immunology.  

Position Summary

The Research Scientist will join a dynamic Precision Oncology team to apply Aitia’s powerful Causal AI platform to oncology drug discovery and clinical development.  The candidate will work closely with scientists at major biopharma and emerging drug discovery companies to deliver unique scientific insights for decision making.

The candidate will be responsible to work with internal and external teams to formulate scientific questions into coherent analytical efforts for causal analysis and derive novel biological insights for disease mechanism and to develop prognostic and predictive biomarkers.   The candidate will carry out these projects using Aitia’s proprietary Causal AI modeling and simulation platform and synthesize these results with relevant literature and bioinformatics resources.  They will communicate scientific findings to partners and collaborators and contribute to presentations at scientific conferences and publications.

Principal Duties and Responsibilities:

• Work as part of internal research teams to collaborate with clients to frame research questions, propose solutions, conduct analyses, and prepare reports
• Contribute to cross-team efforts(e.g. business, IT, and R&D) to build in silico patient causal AI models and research into novel model applications for oncology therapeutic discovery
• Manage and complete external facing projects of high complexity in a timeline driven manner
• Contribute to novel cancer genomics knowledge generation through deep data mining from public/proprietary multimodal datasets
• Communicate technical results clearly and concisely to collaborators, discuss how to incorporate information into their processes, and achieve high client satisfaction
• Maintain expertise in state-of-the-art data science and cancer genomics methods

Job qualifications:

Advanced degree in quantitative science or life science with experience in the area of cancer genomics

• Solid understanding of statistical analysis principles and expert-level knowledge in data analysis with R/Bioconductor or Python 
• Experience with analysis, evaluation and QC of multi-omics data, single cell data, and high-throughput screening data
• Familiarity with major cancer genomics / bioinformatics databases(e.g. TCGA, DepMap etc.) and tools
• Experience working with advanced ML techniques, probability theory, Bayesian analysis, or causal inference methods preferred
• Preferably, prior experience working with preclinical drug discovery work
• Team player willing to help and ask for help; excellent written and verbal communication skills;  excellent interpersonal skills with a proven record of effective cross-disciplinary collaboration

Company Culture

Our philosophy at Aitia is simple: we cannot transform drug discovery and development with anything less than an all-star team. We are seeking smart, driven people who are experts in their field, have a track record of success, and a passion for creating change. We believe that strong teams supercharge the performance of individuals, create a fun and dynamic workplace, and provide first-class results for our clients and the people they serve. We are passionate about our work and believe in the ability of our technology to change the world. Our core values of integrity, collaboration, value, diversity, and game-changing initiatives guide our behaviors with each other and our clients. Aitia offers competitive salaries, stock options, unlimited vacation, health, dental and vision insurance, life insurance, long-term disability, 401(k), parental leave, tuition reimbursement, professional development, subsidized parking/MBTA pass, tasty food, volunteering opportunities, social gatherings, and more. 

Equal Employment Opportunity

Aitia provides equal employment opportunities to all employees and applicants for employment without regard to race, color, national origin, religion, sexual orientation, gender, gender identity or expression, age, veteran status, disability, pregnancy or conditions related to pregnancy, or genetics. In addition to federal law requirements, Aitia complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities.

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