Scientific Associate Director - Toxicology - Bristol Myers Squibb
Brisbane, CA
About the Job
Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
This is a Hybrid role
Nonclinical Safety (NCS), within Nonclinical Research and Biotherapeutics, is responsible for designing and implementing overall nonclinical safety strategy to support the development and eventual marketing approval and post-marketing safety for the breadth of the BMS portfolio in oncology, hematology, cardiovascular disease, fibrosis, immunology and neurology. Located in any of our sites (New Brunswick, Lawrenceville, Princeton, NJ; San Diego, Brisbane, CA; Cambridge, Mass; Seattle, WA) NCS members work with discovery and development colleagues, as well as health authorities across the country and the world, to bring innovative and impactful medicines to patients around the globe.
Position Overview
In the role as a Project Toxicologist , the ideal candidate:
+ Is responsible for the oversight of the nonclinical safety-evaluation programs for selected drug candidates.
+ Assists in the proper design and timely reporting of exploratory and pivotal toxicity studies, including single- and repeat-dose toxicity, investigative toxicity, and other toxicity studies.
+ Act as a Nonclinical Safety representative on early- and late-stage project development teams.
+ Provides scientifically and strategically sound nonclinical development plans to management and development teams.
+ On an as-needed basis, interacts with regulatory agencies worldwide on issues of nonclinical safety evaluation.
+ Writes and critically reviews submission documents, such as CTD sections for INDs and NDAs, IBs, PIPs, briefing books to support clinical trials and drug registration globally.
+ Participates in discussions with internal development teams and/or regulatory agencies to address safety findings and provide safety assessments.
+ Evaluates, proposes, and applies new scientific methodology to enhance scientific excellence and/or productivity in Nonclinical Safety. Works collaboratively across disciplines to identify, characterize, and resolve target/compound based toxicities.
+ Represents BMS in external scientific and regulatory collaborations, committees and consortia.
+ Gains broad-based exposure to the various functional areas within Nonclinical Safety with an opportunity to perform independent research as appropriate.
+ Collaborates with the Discovery organization to help evaluate toxicity of drug candidates.
+ Ensures compliance with Good Laboratory Practice, Standard Operating Procedures, and study protocols in conducting nonclinical studies, when applicable. Ensures compliance with all company/departmental policies, particularly those relating to animal welfare and safety.
+ Embraces/demonstrates BMS Core Values to create an atmosphere of scientific excellence, open communication, and creativity in order to maximize productivity.
Basic Qualifications:
+ 12+ years of academic / industry experience
+ Or Master's Degree 10+ years of academic / industry experience
+ OR PhD 8+ years of academic / industry experience 4+ years of leadership experience
Preferred Qualifications
+ 10+ years regulatory toxicology/development experience.
+ Knowledge of biochemical and mechanistic toxicology, immunology, pharmacology, biology of disease, and/or experimental pathology. Experience designing and interpreting in vitro and in vivo studies exploring mechanisms of toxicology involving biochemical, immunological, functional, molecular, and/or structural endpoints.
+ Effective written and oral communication skills, especially as they pertain to writing clear, and accurate documents and presenting data.
+ Individual must be able to manage multiple research activities, provide and accept input on data interpretation, foster a spirit of team effort, and be able to work well with others.
+ Ability to interpret and apply available toxicity data to assess relative risk or hazard to humans.
The starting compensation for this job is a range from $185,000 to $231,300, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final , individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site. Life At BMS - BMS Careers (https://careers.bms.com/life-at-bms/)
Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.
#LI-Hybrid
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Company: Bristol-Myers Squibb
Req Number: R1584005
Updated: 2024-09-20 04:55:50.817 UTC
Location: Princeton-NJ
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
This is a Hybrid role
Nonclinical Safety (NCS), within Nonclinical Research and Biotherapeutics, is responsible for designing and implementing overall nonclinical safety strategy to support the development and eventual marketing approval and post-marketing safety for the breadth of the BMS portfolio in oncology, hematology, cardiovascular disease, fibrosis, immunology and neurology. Located in any of our sites (New Brunswick, Lawrenceville, Princeton, NJ; San Diego, Brisbane, CA; Cambridge, Mass; Seattle, WA) NCS members work with discovery and development colleagues, as well as health authorities across the country and the world, to bring innovative and impactful medicines to patients around the globe.
Position Overview
In the role as a Project Toxicologist , the ideal candidate:
+ Is responsible for the oversight of the nonclinical safety-evaluation programs for selected drug candidates.
+ Assists in the proper design and timely reporting of exploratory and pivotal toxicity studies, including single- and repeat-dose toxicity, investigative toxicity, and other toxicity studies.
+ Act as a Nonclinical Safety representative on early- and late-stage project development teams.
+ Provides scientifically and strategically sound nonclinical development plans to management and development teams.
+ On an as-needed basis, interacts with regulatory agencies worldwide on issues of nonclinical safety evaluation.
+ Writes and critically reviews submission documents, such as CTD sections for INDs and NDAs, IBs, PIPs, briefing books to support clinical trials and drug registration globally.
+ Participates in discussions with internal development teams and/or regulatory agencies to address safety findings and provide safety assessments.
+ Evaluates, proposes, and applies new scientific methodology to enhance scientific excellence and/or productivity in Nonclinical Safety. Works collaboratively across disciplines to identify, characterize, and resolve target/compound based toxicities.
+ Represents BMS in external scientific and regulatory collaborations, committees and consortia.
+ Gains broad-based exposure to the various functional areas within Nonclinical Safety with an opportunity to perform independent research as appropriate.
+ Collaborates with the Discovery organization to help evaluate toxicity of drug candidates.
+ Ensures compliance with Good Laboratory Practice, Standard Operating Procedures, and study protocols in conducting nonclinical studies, when applicable. Ensures compliance with all company/departmental policies, particularly those relating to animal welfare and safety.
+ Embraces/demonstrates BMS Core Values to create an atmosphere of scientific excellence, open communication, and creativity in order to maximize productivity.
Basic Qualifications:
+ 12+ years of academic / industry experience
+ Or Master's Degree 10+ years of academic / industry experience
+ OR PhD 8+ years of academic / industry experience 4+ years of leadership experience
Preferred Qualifications
+ 10+ years regulatory toxicology/development experience.
+ Knowledge of biochemical and mechanistic toxicology, immunology, pharmacology, biology of disease, and/or experimental pathology. Experience designing and interpreting in vitro and in vivo studies exploring mechanisms of toxicology involving biochemical, immunological, functional, molecular, and/or structural endpoints.
+ Effective written and oral communication skills, especially as they pertain to writing clear, and accurate documents and presenting data.
+ Individual must be able to manage multiple research activities, provide and accept input on data interpretation, foster a spirit of team effort, and be able to work well with others.
+ Ability to interpret and apply available toxicity data to assess relative risk or hazard to humans.
The starting compensation for this job is a range from $185,000 to $231,300, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final , individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site. Life At BMS - BMS Careers (https://careers.bms.com/life-at-bms/)
Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.
#LI-Hybrid
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Company: Bristol-Myers Squibb
Req Number: R1584005
Updated: 2024-09-20 04:55:50.817 UTC
Location: Princeton-NJ
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.
Source : Bristol Myers Squibb
