Scientist, API Upstream Process Development - Johnson and Johnson

Janssen Research & Development, LLC, a Johnson & Johnson Company, is hiring a Scientist, API Upstream Process Development to be located in Malvern, PA.

At Janssen, we never stop working toward a future where disease is a thing of the past. We're the Pharmaceutical Companies of Johnson & Johnson, and you can count on us to keep working tirelessly to make that future a reality for patients everywhere, by fighting sickness with science, improving access with ingenuity, and healing hopelessness with heart. We focus on areas of medicine where we can make the biggest difference: Cardiovascular & Metabolism, Immunology, Infectious Diseases & Vaccines, Neuroscience, Oncology, and Pulmonary Arterial Hypertension. Visit us: www.janssen.com

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to Diversity & Inclusion, Janssen Research & Development, LLC is proud to be an equal opportunity employer.

The successful candidate for this position will contribute to upstream process development within the therapeutic protein process development group in Malvern, PA. The candidate will be responsible to lead and perform upstream process development studies including:

• Lead and participate in design of experiments
• Plan and guide study execution
• Lead and participate in control strategy development
• Lead and participate in tech transfer, facility fit, and process scale up/ scale down
• Plan and execute process validation studies (laboratory and manufacturing-scale)
• Record and analyze data
• Author and review technical reports

Additional duties include:

• Lead and participate in scientific investigations and trouble-shoot process issues that arise during development, technology transfer, or scale-up
• Contribute to regulatory filings
• Participate in technology development
• Coordinate laboratory training initiatives,

The candidate is expected to work effectively in a team environment and well as contributing individually to meet project objectives and timelines. Other duties will be assigned, as necessary.Education:

• A PhD in Biological Sciences or Cell Biology or Biochemistry or Chemical Engineering OR a Masters with at least 6 years of experience performing progressively advanced duties at the Senior Associate Scientist level OR equivalent training and relevant experience is required

Experience and Skills:

Required:

• Knowledge of and hands-on experience with cell culture media characterization and/or optimization is required
• Hands-on experience with laboratory scale cell culture bioreactor equipment and instrumentation is required
• Knowledge of large molecule drug substance (API) upstream manufacturing process development is required
• Highly organized and capable of managing/pursuing multiple projects is required
• Good written and verbal communication skills are required
• Experience maintaining written records of work in the form of laboratory notebooks (paper or electronic) is required
• The ability to report data, present findings to management is required
• Experience with team-based collaborations and direct management of staff is required
• Occasional domestic or international travel will be required

Preferred:

• Familiarity with and hands-on experience with analytical methods typically used in the manufacture and characterization of recombinant proteins is preferred

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com