Scientist, Bioinformatics at Regeneron Pharmaceuticals, Inc.

The Molecular Profiling and Data Science Department at Regeneron is seeking an enthusiastic and rigorous scientist who values independent research in an open and collaborative work environment.

In this role, a typical day might include:

• The candidate will operate at the interface of dry and wet-lab environments, leading software development and bioinformatic analyses to help the Regeneron Genetics Medicines department create next-generation gene therapies (gene editing, suppression, expression, and insertion).

• They will contribute to cutting-edge technologies such as AAVs, si/shRNAs, LNPs, and CRISPR-Cas9 to treat and cure diseases.

• The candidate will be part of a group consisting of computational scientists with backgrounds ranging from biology to physics with knowledge in genomics and machine learning.

• They will work closely with the NGS team and wet-lab scientists across Regeneron to create genetic therapies for a wide range of diseases.

This role might be for you if can:

• Design, generate and interpret high dimensional data from key platform technologies to support the Regeneron Genetic Medicines department develop novel genetic therapy strategies.

• Develop, implement and utilize pipelines in R and/or Python to carry out a range of bioinformatic analyses on large volumes of omics data.

• Set priorities and ensure project completion within pre-defined timeframes.

• Present results to internal stakeholders, publish in peer-reviewed journals, participate in cross-functional meetings and external activities, and contribute to patent and regulatory filings.

The ideal candidate will have a combination of:

• Experience with NGS, as well as experimental wet-lab molecular biology and genetic techniques, such as cloning and CRISPR.

• Experience extracting biological insights from transcriptomics, genomics, and other omics datasets at the single-cell and bulk level.

• Demonstrated experience with applying statistics, especially machine learning models, to answer biological questions.

• Familiarity with a Linux environment, shell scripting, and high-performance computing clusters.

To be considered for this opportunity, you must have the following:

• A BSc + 2 years of industry experience, or an MSc in Quantitative Biology, Bioinformatics, Computational Biology, Systems Biology, or related field.

• Hands-on experience developing and using bioinformatic tools to analyze omics datasets.

• Ability to apply quantitative reasoning when analyzing data, with an appropriate understanding of the assumptions and models used to make inferences.

• Excellent presentation and interpersonal communication skills, allowing you to engage with diverse audiences and navigate between high-level motivations and technical details.

• An independent, problem-solving mindset, with the capacity to introduce novel bioinformatic pipelines and dive deep into data while balancing different internal priorities from diverse preclinical programs.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)