Scientist - II (Associate) - Automation / Liquid Handler - On-Board Companies

Position Details:
Position Type: Scientist II – Automation / Liquid Handler
Job Location: Boston, MA
Compensation: $33.80 per hour
Length of Assignment: 1 year with a possibility of extension

This is an exciting opportunity in the Biochemistry and Biophysics Group within the Department of Pharmacology

Key skills/must haves:

Requirements:
The responsibilities of the candidate include but are not limited to:

• Previous Automation and Liquid Handling experience clearly written on the resume.
• Develop and/or run quantitative biochemical and biophysical assays to support identification, characterization, and optimization of small molecule ligands from high throughput screening campaigns and medicinal chemistry efforts.
• Conduct biochemical and biophysical studies to elucidate the modes of ligand interaction and mechanisms of action on target proteins.

Qualifications:

• BS/BA degree in biochemistry, biophysics or a related discipline with a minimum of 3-5 years industry experience; or a MS degree in biochemistry, biophysics or a related discipline with 2 or more years of industry experience, preferably with a focus on assay development and compound profiling within a drug discovery environment.
• Candidate should have basic knowledge of biochemistry, biophysics and molecular biology
• Candidate should have prior experience with basic biochemical and/or biophysical techniques
• Candidate should be highly motivated, driven, and willing to take the initiative to learn new scientific methodologies
• Candidate should be a strong team player
• Candidate should have excellent oral and written communication skills
• Candidate should be comfortable using a PC computer and proficient in Windows-based operating systems and basic applications, such as spreadsheets and databases
• Experience in the use of automated liquid handlers such as Echo, Bravo, Biomek, or Hamilton and data analysis and presentation software such as TIBCO Spotfire, Excel and PowerPoint.

Preferred Experience and Skills:

• Proven ability to independently design, develop and implement biochemical and biophysical screening assays using detection modalities such as: TR-FRET, FP, LC-MS, radiochemical, surface plasmon resonance (BIAcore), fluorescence-based thermal shift (TdF), and/or isothermal titration calorimetry (ITC).
• Hands-on experience performing steady-state and transient-state kinetic experiments to study enzymes and inhibitors.
• Direct experience in recombinant protein expression using bacteria, insect (baculovirus) and/or mammalian cell-based systems and purification using automated chromatographic separation systems.

Apply Today!
www.onboardusa.com

On-Board was founded in 1976 by Robert L. Wilson to provide Engineering and Design services to the chemical manufacturing industry. Today, On-Board is a thriving privately held family of companies with services including: Consulting, Professional Engineering, Industrial Maintenance and Facility Management, Contracted Manufacturing and Production Services, as well as Temporary Staffing and Recruiting throughout North America.

The On-Board Family of Companies conducts operations through its Corporate Headquarters located in East Windsor, NJ along with Regional Offices in New Castle, DE and Wake Forest, NC. On-Board’s Mission is to provide “Flexible Service by applying the talents of our people, work processes and technology to meet our clients’ expectations in a Safe, Responsible and Dependable manner.”

On-Board Companies provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, religion, sex, national origin, age, disability or genetics.

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