Scientist, Immunopeptidomics & Mass Spectometry at Moderna, Inc.

The Role

Moderna is seeking a talented and motivated Scientist of Immunopeptidomics and Mass Spectrometry to join our Cancer Vaccine Research (CVR) team to support research efforts across discovery and pre-clinical initiatives. The ideal candidate will have a background in the field of mass spectrometry-based proteomics.This position requires understanding of instrumentation as well as sample processing and data analysis workflows. The candidate should also possess a passion for innovation and a commitment to advancing transformative medicines in the fight against cancer.

Heres What Youll Do

• Perform sample preparation, nano-liquid chromatography-mass spectrometry (nLC-MS) data acquisition, as well as data analysis and data interpretation to aid in the discovery and validation of tumor-associated antigens and neoantigens

• Take part in regular upkeep of instruments and perform system suitability evaluations

• Consistently update a lab notebook to ensure accurate documentation of experiments, observations, and results

• Maintain up-to-date knowledge of literature in the field proteomics, immunopeptidomics, and cancer vaccines

• Guide and mentor team members

• Collaborate with other research teams to integrate immunopeptidomics and proteomics data into their research areas

• Contribute to the reviewing and writing of scientific manuscripts and IND reports

• Present findings at internal meetings and represent Moderna at scientific conferences

Heres What Youll Need (Basic Qualifications)

• Ph.D. degree in Immunology, Biochemistry, Molecular Biology, or a related field

• Extensive experience with proteomic sample processing workflows including protein digestion, pull-down assays (affinity-tag or immunoprecipitation), and peptide desalting and fractionation

• Extensive experience operating nano-liquid chromatography-mass spectrometry (nLC-MS) systems, with expertise in data acquisition method generation

• Expertise with routine instrument maintenance and troubleshooting

• Expertise with bioinformatics tools and software used for mass spectrometry data analysis

• Ability to manage multiple projects in a fast-paced environment with aggressive timelines

• Excellent interpersonal and communication skills, with a collaborative mindset and the ability to build strong relationships with internal and external stakeholders

• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative

• A passion for innovation and the mission of developing transformative medicines in the fight against cancer

• This role is based in our new LEED-certified HQ in Cambridge, MA and is expected to be in office 70% of the time with flexibility to work from home up to 30%.

Heres What Youll Bring to the Table (Preferred Qualifications)

• Experience with immunopeptidomics workflows

• Hands on experience with quantitative mass spectrometry assays

• Familiarity with Bruker timsTOF instruments and PASEF data acquisition methods

• Proficiency with the following software programs: R, Python, FragPipe, Spectronaut, and Skyline

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  Vacation, sick time and holidays
  Volunteer time to participate within your community
  Discretionary year-end shutdown
  Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, theinfrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our peopleare the driving force behind our scientific progress and our culture.Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. Were focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com. (EEO/AAP Employer)

-