Senior Manager/Associate Director, Clinical Pharmacology - Karyopharm Therapeutics Inc.
Newton, MA 02459
About the Job
Play a pivotal role in analyzing oncology clinical data and driving the planning and execution of innovative clinical pharmacology studies and initiatives.
Reporting to the Vice President, Clinical Pharmacology, you will positively impact patients’ when you:
- Assist in the design, execution, and in-depth analysis of cutting-edge clinical pharmacology studies, encompassing population pharmacokinetics (PK) and exposure/response modeling.
- Perform quantitative pharmacology analyses and contribute to the interpretation of study results.
- Take a lead role in preparing and meticulously reviewing clinical pharmacology sections of study protocols, reports, and regulatory submission documents.
- Work with cross-functional teams, including Biostatistics, Clinical Operations, Translational Science, and Regulatory Affairs, to achieve project goals and support pharmacology objectives.
- Apply pharmacometrics techniques to support drug development and address scientific questions
- MS, PharmD, or PhD in biological or pharmaceutical sciences, with a focus on pharmacometrics and statistics.
- Minimum 4 - 5 years of experience in clinical pharmacology and pharmacometrics, with hands-on experience in quantitative analysis.
- Proficiency with pharmacometrics software, strong analytical abilities, and effective communication skills.
- Understanding of clinical pharmacology study design, data analysis, and regulatory requirements.
At Karyopharm, we live and demonstrate our ICARE values every day!
If you want to do something that matters, this work matters. Patients drive our passion to pioneer novel cancer therapies. That’s why we’ve built an environment centered around support, flexibility, and a shared mission.
Creating and delivering medicine for cancer can only be done through focus, dedication, and heart. We hire exceptional people and trust each other to work in whatever way lets us, be us – whether that’s onsite, from home, or anywhere in between.
What do you get when you pair an extraordinary mission with a culture of flexibility and empowerment? We invite you to find out and join us on this incredible mission.
Check out our Culture Video!
What We Offer:
In addition to our exciting, supportive, and intellectually challenging global workspaces(s), team members enjoy a comprehensive and generous benefits package (active on day one) that makes them more productive and contributes directly to the development of their professional skills.
- A culture of employee engagement, diversity, and inclusion
- Competitive salary, bonus, and generous equity offerings (RSU’s at time of offer and annual awards) – we are partners in prosperity!
- Peace of mind through best in class medical (deducible paid by KPTI), dental, vision, disability, and life insurance, parental leave, a matching 401k program (immediate vesting), ESPP and tuition reimbursement.
- Wellness Program with a monthly stipend.
- Generous PTO and Holidays – we encourage you to recharge and spend time with family and friends.
- Ample opportunities to learn and take on new responsibilities in a fast-paced, and patient focused company. (tuition reimbursement, management development & mentoring programs, and a variety of reward and recognition programs)
- Cell phone allowance
- In the U.S., the salary range for this position is $160,000 to $190,000 per year, which factors in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors