Senior NGS Data Analyst at Regeneron Pharmaceuticals, Inc.

We are seeking a Senior NGS Data Analyst to join our Regeneron Genetic Center's (RGC) Genome Informatics team to provide high-level support to R&D and QC efforts through engineering and research analysis. These efforts span the RGCs full sequencing fleet (e.g. Illumina, Ultima, PacBio) and production informatics portfolio, including ultra-large scale genomics and multiomics on the RGCs 2.5M+ samples. Under the direction of the Production Sequencing Informatics R&D Lead, you will develop and execute analysis code to perform a variety of research tasks including evaluation of new sequencing assays, productionization of new methods, and analysis of existing data to improve QC and production performance. We hope you are excited by this opportunity to translate research questions and data into code and results.

As a Senior NGS Data Analyst, a typical day might include the following:

• Designing computational experiments to inform Sequencing R&D efforts and then perform the coding, testing, and execution of the experiment and the analysis of the results, with the support of the R&D lead

• Maintaining extensive data standards and resources to enable rapid, large-scale validation of sequencing analysis updates

• Creating visualizations and present to genome informatics and data engineering leads the results of these experiments, synthesizing feedback for subsequent iterations

• Developing production quality tools to support R&D efforts

• Working with the Engineering Lead, ensure all code, documentation and methods meet production standards

This job might be for you if:

• You have an interest in the health & life-sciences data domain and a passion to bring innovative technologies in the field

• You are thorough and focus on the quality of the final product

• You enjoy collaborating with multi-functional teams of scientists, analysts, and engineers

• With your sleeves rolled up, you work on current problems while thinking of future solutions

In order to be considered for this role, you must have a Bachelors in Computer Science or Bioinformatics with 4+ years of relevant experience in genome informatics (or Masters with 2+ years' experience). We need someone with strong expertise with Unix and Python. Mastery of software development standard processes including code repositories (GitHub, Sourceforge, Bitbucket), software development life cycle, version control, testing is required. Must have experience with NGS tools, methods and formats (Samtools, BCFtools, VCFtools, BWA, GATK, Picard, BEDtools, PLINK). We need someone with a strong understanding of NGS and genomics research concepts. Must have proficiency in Unix- and cloud-based compute environments (DNAnexus preferred). Experience with data visualization (Pandas or R) required.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)