Senior Scientist II, Ophthalmology at AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.

The Ophthalmology Discovery group at AbbVie is seeking a Senior Scientist II responsible for the design and implementation of pre-clinical in vivo studies to identify, validate, and characterize potential therapeutic targets and assets to support ophthalmic drug discovery and development programs. The candidate will lead and contribute to the implementation of strategies for the discovery and validation of targets in ophthalmology. As a member of multidisciplinary teams, the candidate will be responsible for developing and implementing innovative translatable large animal models of retinal and optic nerve diseases with clinically relevant endpoints. The candidate will be responsible for generating disease models using surgical, laser, drug, chemical, or genetic techniques and select and optimize appropriate endpoints. Additionally, the candidate will be responsible for data collection and analyses, interpretation, and reporting of results of nonclinical in vivo pharmacology studies. The successful candidate is expected to collaborate with peers in multidiscipline programs or project teams and to advise and consult with other scientists in R&D as well as outside collaborators. The candidate should have a track record of cross-functional collaborations along with excellent written and oral communication skills.

Specific responsibilities:

• Design and conduct in vivo nonclinical pharmacology studies.
• Analyze, interpret, and report in vivo pharmacology datasets.
• Provide input to drive decisions to advance Discovery projects.
• Provide subject matter expertise in animal models of ocular diseases and ocular and visual functions.
• Advise and consult with other scientists in R&D as well as outside collaborators.
• Active scientific participation and collaboration with colleagues in industry and academia

• Neuroscientist or Vision Scientist with BS (+12 yrs experience), MS (+10 yrs experience) or Ph.D. (4 yrs experience)
• Expertise in models of ophthalmic disease, functional vision assessments, and ophthalmic imaging modalities, as well as the application of these techniques to pharmacological studies
  • Experience with a range of ocular imaging modalities, including angiography and autofluorescence, fundus and vitreal photography, ocular coherence tomography (OCT), slit lamp biomicroscopy, gonioscopy, specular microscopy, ultrasonography, and ophthalmoscopy is highly desired
  • Knowledge of functional in vivo endpoints including vision psychophysics, ocular electrophysiology (ERG, VEP) is highly desired.
• Must be able to multitask effectively and be adaptable and flexible to meet changing priorities.
• Committed to the values of integrity, accountability, transparency, scientific rigor, and drive.
• Effective written and verbal communication skills required.
• Excellent collaboration and team skills are required.
• The successful candidate is required to have the ability to work within a diverse workforce.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible to participate in our short-term incentiveprograms.

• This job is eligible to participate in our long-term incentiveprograms

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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