Sr. Associate Scientist – Peptide Discovery (San Diego, CA) at Eli Lilly and Company

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

General Description

This is a technical position in the Peptide Discovery Team within Lilly Biotechnology Center in San Diego.  The individual should demonstrate expertise in molecular biology, in vitro assay development and/or display technologies.  The candidate will be an integral part of an innovative and interdisciplinary team that utilizes phage and mRNA display platforms to enable de novo peptide discovery at Lilly.  The successful candidate must show a track record of innovation behavior, scientific curiosity, and desire to learn and implement new technologies and platforms. Excellent interpersonal, communication, and organizational skills are required for this position. 

Key objectives and deliverables
 

Support the peptide discovery team in the build and execution of phage and mRNA display selections to identify target specific peptide therapeutics.  Routinely prepare reagents for phage and mRNA display selections including peptide libraries, components of in vitro translation system, aminoacyl-tRNAs and buffers. Collaborate and effectively communicate with project teams, cross-functional teams, and the Peptide Discovery team members.  Present data on regular basis in various internal meetings Diligently maintain detailed, and well-organized records of experiments using Electronic Notebooks

Requirements

• B.S. in Biology, Chemistry or a related field with at least 2 years of industry experience OR M.S. in Biology, Chemistry or a related field

• Strong hands-on experience in basic biochemical and molecular biology techniques

Additional Preferences

• Knowledge and experience in PCR, DNA/RNA preparation & purification and ELISA

• Knowledge and experience in Flexizyme technology, mRNA display and/or Phage display platforms

• Knowledge and experience in cloning, cell-culture and protein expression & purification

• Knowledge and experience in FACS and flow cytometry.

• Self-motivated, strong work ethic, independent and results oriented.

• Ability to work independently as well as in cross-functional team settings.

• Self-driven, imaginative, organized, focused, and able to work as part of a high-performing, high-paced team

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