Sr. Medical Director, Neurology at Alumis Inc.

Alumis Inc is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer – our goal is to fundamentally change the outcomes for these patients.

We are seeking an experienced medical professional to serve as the Senior Medical Director, Neurology, reporting to the SVP of Clinical Development. The successful individual will play a pivotal role in advancing our A-005 clinical program through Phase 1 and initiating the Phase 2 program in multiple sclerosis. You will provide leadership and contribute to the strategic planning, execution, and management of the MS program, collaborating closely with cross-functional teams, while driving the clinical development strategy, and providing clinical and scientific leadership in the development A-005, a first in class, CNS-penetrant, oral, allosteric TYK-2 inhibitor designed to treat neurologic diseases.

RESPONSIBILITIES:

· Broadly represent the interests of Alumis as a senior leader and spokesperson for Clinical Development within the field of Neurology

· Provide leadership in the management and oversight of the Phase 1 and 2 studies with A-005

· Cultivate and maintain relationships with key opinion leaders and external stakeholders to advance clinical development programs and enhance company visibility.

· Effectively influence cross-functional teams within Research, Biomarkers, Medical Affairs, Commercial, Regulatory and Business Development as an expert within the Neurology therapeutic area and broadly across immune mediated inflammatory diseases (IMID)

· Design and develop clinical studies and cross-functional initiatives

· Provide strategic support and implement clinical strategies across early and late-stage clinical development programs

· Closely interface with early development groups to define opportunities to explore new areas for scientific inquiry, including new indications and line extensions for molecules across the development pipeline

· Collaborate with colleagues from Business Development on due diligence opportunities that support both early and late-stage development collaborations, as well as co-development opportunities with external companies.

· Coach, manage, inspire, and support team members to achieve business goals by leveraging an entrepreneurial and collaborative mindset

· Maintain the highest levels of integrity within development and standards for scientific inquiry in drug development

· Collaborate with CRO to provide medical monitoring oversight for the Phase 2 program

QUALIFICATIONS AND SKILLS REQUIRED:

· MD or ex-US equivalent with board certification or eligibility in Neurology with > 5 years of drug development experience within a medium to large biopharmaceutical company leading a development program in multiple sclerosis

· Clinical development experience extending to Phase 1 clinical with small molecules

· Noted R&D expert with credibility to interface with Key Opinion Leaders, external health organizations and regulators within Neurology

· Proven leadership skills, as evidenced by having managed people within a pharmaceutical company or in a clinical/academic environment

· Ability to interact effectively in a cross-functional setting

· Strong interpersonal, influencing, presentation, and communications skills (written and verbal) to effectively address all levels within an organization

· Ability to assess, understand, and communicate continuously expanding medical and scientific information, as well as knowledge of commercial dynamics impacting drug development

· Strong business acumen and ability to collaborate with cross-functional partners to achieve enterprise goals

· Effective negotiation skills that enable the candidate to influence without authority

· Proven professional track record of strategic, organizational, and executional skills to support project planning across multiple activities, with the ability to anticipate and prioritize one’s workload across multiple projects of equal importance

· Ability to work across diverse teams in a matrixed organizational structure, both as a leader and as part of a cross-functional team

· Approaches deliverables in an organized manner with attention to detail and is able to meet timelines in a fast-paced environment

· Able to work autonomously and with a high level of independence

ALUMIS VALUES:

· We Elevate

· We Challenge

· We Nurture

This position is located in South San Francisco, CA. At this time, we are not considering fully remote applicants.

The salary range for this position is $325,000 USD to $358,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.

Alumis Inc. is an equal opportunity employer.