Sr Scientist, Therapeutic Antibody Discovery at Regeneron Pharmaceuticals, Inc.

We are seeking a motivated Scientist to join our Human Antibody Isolation Team, which contributed to the development of Regenerons SARS-CoV-2 antibody cocktail (REGEN-COV). You will play an integral part in the identification of antibodies to treat diseases with unmet medical needs. The primary functions of this position include the isolation of monoclonal antibodies from human donors against diverse disease targets (e.g., infections, allergy and immune disorders) and the development of new antibody isolation technologies and cloning techniques. Some experiments will require harvesting of lymphoid tissues from mice. We are looking for a team player who is experienced with cell culture and flow cytometry, eager to learn, and will utilize cutting-edge techniques for the development of the next generation of therapeutic antibodies.

A Typical Day May Include:

• Isolating PBMCs from human peripheral blood
• Performing cell enrichment, cell culture, cell differentiation, antibody staining, and phenotypic characterization
• Independently designing, conducting, and analyzing multicolor flow-cytometry experiments
• Harvesting mouse spleen, lymph nodes, and bone marrow
• Optimizing and carrying out functional assays such as ELISA and Luminex
• Performing molecular biology experiments, including DNA/RNA purification, RT-PCR, molecular cloning, and western blot
• Analyzing and presenting data in a team-based setting
• Maintaining complete, accurate, and timely records of experiments and data analysis
• Contributing to lab equipment maintenance and ordering supplies/reagents to help create a safe, effective, and efficient working environment

This Job May Be For You If:

• You are able to work independently, demonstrating strong problem-solving skills and the ability to manage multiple tasks efficiently without direct supervision.
• You can work in a collaborative, fast-paced environment.
• You have a strong desire to develop your skills and work with cross functional team

To be considered for this position, you should have a PhD with 0-3 years of postdoctoral experience, or a BS/MS with 4-8 years of experience in Immunology, Cell Biology, and/or Molecular Biology. Hands-on technical experience in cell culture, PBMC isolation, flow cytometry, or antibody staining is necessary. Experience with functional assays such as ELISA and ELISPOT, as well as molecular biology techniques like PCR and cloning, is a plus. You should be comfortable handling mice. The level of the position will be commensurate with your experience.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)