Stem Cell Research Associate (Contract) - Vertex Pharmaceuticals

Research Associate – Developmental Biology of Stem Cells derived Islets (SC-Islets)

Position Summary:

Vertex seeks a talented research associate to join the Vertex Cell and Genetic Therapies (VCGT) stem cell research group in Boston, MA. The group’s mission is to discover and actualize the next generation of cell therapies for diabetes.

We are looking for a candidate with a background in stem cell and developmental biology, interested in understanding the cell and molecular mechanisms by which cells differentiate.

Candidates must have strong cell culture skills and familiarity with analytical methods in cell and molecular biology.

The candidate will work closely with our scientists on discovery projects advancing our capabilities in pluripotent stem cell-derived therapies. The ideal candidate is a motivated, critical thinker willing to take initiative. This position requires strong communication and organizational skills, and candidates must be able to work well in a highly collaborative environment.

Key Responsibilities:

• Perform human pluripotent stem cell culture and support discovery research efforts in stem cell biology
• Perform directed differentiation experiments of human pluripotent stem cells to pancreatic islets to support discovery research efforts.
• Follow protocols and contribute to stem cell differentiation campaigns (periodic weekend work is required).
• Work with cross-functional teams to plan, coordinate, and execute experiments.
• Present findings to the group and broader disease area teams and summarize data into reports for the supervisor.
• Assist with lab management: track cell culture reagents, place orders, prepare media and reagents, and continuously work to improve lab operations.

Scientific and Non-Scientific Skills:

• Strong mammalian cell culture experience is required; pluripotent stem cell culture experience (e.g., hESC and/or hiPSC) in 2D and/or 3D is desirable.
• Experience performing stem cell differentiation to any cell type is preferred.
• Technical skills should include experience with many of the following: cell-based assays such as flow cytometry, western blotting, gene expression (qPCR, nanostring, etc.), and immunocytochemistry.
• Must possess critical thinking, self-reliance to solve tasks independently, and a willingness to ask questions.
• The successful candidate will have outstanding organizational and multitasking capabilities.
• Candidate must possess flexibility to quickly pivot as projects demand.
• The candidate will be accustomed to effectively communicating progress, needs, and problems.

Preferred Education and Experience Levels:

• BS 0-2+ years of relevant experience

$33-$35/HR

This job posting is for a temporary role with a third-party agency partner on assignment at Vertex Pharmaceuticals (“Vertex”). The individual selected for this role will be offered the role as an employee of a third- party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements

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