Summer 2025 - Quantitative systems Pharmacology & Physiologically Based Pharmacokinetics Internship - Bristol Myers Squibb
Princeton, NJ
About the Job
Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
Position Summary
We are seeking passionate and skilled college and graduate students who look for opportunities to learn, to grow, and work alongside talented career QSP&PBPK scientists. The Intern will work in BMS Clinical Pharmacology, Pharmacometrics, and Bioanalysis (CPPB) Department with specific focus on mechanistic modeling projects, under the guidance of a scientist experienced in the development and improvement of models. Depending on the projects prioritized by the advisors and the department, the intern may have different specific goals. Potential projects include but are not limited to the assessment and development of methods for efficient characterization and prediction of small molecule absorption, distribution, metabolism, excretion, and drug-drug interactions; development of new models for other modalities; or developing and parameterizing mini-models for other pathways and processes of interest as relevant for discovery, toxicology, and clinical efforts and incorporating them into a platform. The project can involve testing the functionality of the models in the context of different therapies and helping with data analysis to advance research and development programs.
As part of the Bristol Myers Squibb Virtual Intern Program the successful candidate will have cross-functional networking opportunities for personal and professional development.
Potential Responsibilities
+ Develop and parametrize mechanistic models using systems of ordinary differential equations
+ Calibrate parametrized mini-models using in-house data or data available in the public domain
+ Identify and determine physiological range of the most sensitive parameters
+ Incorporate pathway knowledge into platforms and test functionality with respect to existing therapies
+ Assist in the analysis of discovery, toxicology, and clinical data
+ Participate in the BMS Virtual Intern Program activities
Qualifications & Experience
+ Student in mathematics, engineering (chemical, biomedical, others), physics, or pharmaceutical disciplines including drug metabolism and pharmacokinetics with strong mathematical background
+ Solid knowledge of modeling using ordinary differential equations and numerical solvers
+ Knowledge of how to perform parameter estimation and sensitivity analysis
+ Experience with MATLAB/SimBiology environment is beneficial
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Company: Bristol-Myers Squibb
Req Number: R1585582
Updated: 2024-10-04 03:11:06.997 UTC
Location: Princeton-NJ
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
Position Summary
We are seeking passionate and skilled college and graduate students who look for opportunities to learn, to grow, and work alongside talented career QSP&PBPK scientists. The Intern will work in BMS Clinical Pharmacology, Pharmacometrics, and Bioanalysis (CPPB) Department with specific focus on mechanistic modeling projects, under the guidance of a scientist experienced in the development and improvement of models. Depending on the projects prioritized by the advisors and the department, the intern may have different specific goals. Potential projects include but are not limited to the assessment and development of methods for efficient characterization and prediction of small molecule absorption, distribution, metabolism, excretion, and drug-drug interactions; development of new models for other modalities; or developing and parameterizing mini-models for other pathways and processes of interest as relevant for discovery, toxicology, and clinical efforts and incorporating them into a platform. The project can involve testing the functionality of the models in the context of different therapies and helping with data analysis to advance research and development programs.
As part of the Bristol Myers Squibb Virtual Intern Program the successful candidate will have cross-functional networking opportunities for personal and professional development.
Potential Responsibilities
+ Develop and parametrize mechanistic models using systems of ordinary differential equations
+ Calibrate parametrized mini-models using in-house data or data available in the public domain
+ Identify and determine physiological range of the most sensitive parameters
+ Incorporate pathway knowledge into platforms and test functionality with respect to existing therapies
+ Assist in the analysis of discovery, toxicology, and clinical data
+ Participate in the BMS Virtual Intern Program activities
Qualifications & Experience
+ Student in mathematics, engineering (chemical, biomedical, others), physics, or pharmaceutical disciplines including drug metabolism and pharmacokinetics with strong mathematical background
+ Solid knowledge of modeling using ordinary differential equations and numerical solvers
+ Knowledge of how to perform parameter estimation and sensitivity analysis
+ Experience with MATLAB/SimBiology environment is beneficial
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Company: Bristol-Myers Squibb
Req Number: R1585582
Updated: 2024-10-04 03:11:06.997 UTC
Location: Princeton-NJ
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.
Source : Bristol Myers Squibb